268 Depression and anxiety in atopic dermatitis vs bullous pemphigoid
نویسندگان
چکیده
Atopic dermatitis (AD) and bullous pemphigoid (BP) are inflammatory skin diseases associated with intense pruritus significant quality of life (QOL) impact. While they differ in classical presentation (eczematous eruption vs urticaria blisters) population characteristics (young-to middle-aged persons elderly), early stages BP can appear similar to AD clinically histologically. As part this observational cohort study, we investigated whether there were differences anxiety depression between the cohorts at baseline over time. This study included 93 patients either (50) or (43) a history chronic pruritus. Our was mostly female (61%), mean ages 47.2 72.2 (BP), severity scores 35.9 (AD, SCORAD) 19.1 (BP, BPDAI). The Hospital Anxiety Depression Scale used measure (HADS-D) (HADS-A). At baseline, had overall higher HADS-D scores, 6.14 ± 4.4 compared 4.33 (p = 0.023) indicating greater depressive symptoms, although HADS-A both “Normal” range (score ≤7). Notably, 31% 16% “Borderline/Abnormal” for 38% 30% anxiety. noted be increased no found follow-up visits BP. There changes HADS time within each cohort. Both (PCC 0.424, p<0.01) 0.235, p=0.038) significantly correlated itch measured using ItchyQuant. important aspects patient care consider such as that greatly impact QOL. Clinicians should particularly mindful it relates severity.
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Background: Bullous pemphigoid (BP) is a chronic, autoimmune blistering skin disease that affects patients' daily life and psychosocial well-being. Objective: The aim of the study was to evaluate the quality of life, anxiety, depression and loneliness in BP patients. Methods: Fifty-seven BP patients and fifty-seven healthy controls were recruited for the study. The quality of life of each p...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2022
ISSN: ['1523-1747', '0022-202X']
DOI: https://doi.org/10.1016/j.jid.2022.05.275